A comparison of the incidence of supraventricular arrhythmias between thoracic paravertebral and intercostal nerve blocks in patients undergoing thoracoscopic surgery: A randomised trial

Eur J Anaesthesiol. 2018 Oct;35(10):792-798. doi: 10.1097/EJA.0000000000000837.

Abstract

Background: Postoperative supraventricular arrhythmias are common in patients after thoracoscopic lobectomy. Inadequate pain control has long been recognised as a significant risk factor for arrhythmias. The performance of ultrasound-guided (USG) thoracic paravertebral block (PVB) is increasing as an ideal technique for postoperative analgesia.

Objective: We conducted this study to evaluate whether a single-shot USG thoracic PVB would result in fewer postoperative supraventricular tachycardias (SVT) than intercostal nerve blocks (ICNBs) after thoracoscopic pulmonary resection.

Design: A randomised controlled study.

Setting: A single university hospital.

Patients: Sixty-eight patients undergoing thoracoscopic lobectomy were randomised into two equal groups of 34.

Interventions: For postoperative pain control, all patients received a total of 0.3 ml kg of a mixture containing 0.5% ropivacaine and 1/200 000 epinephrine after placement of needles for either a single thoracic PVB or two individual ICNBs, both guided by ultrasound. Data were obtained during the first 48 postoperative hours.

Main outcome measures: The primary outcome was the incidence of SVT after thoracoscopic pulmonary resection.

Results: During the first 48 postoperative hours, the incidences of SVT and atrial fibrillation were lower in the USG thoracic PVB group (14.7 vs. 46.9%, P = 0.004 and 3.0 vs. 18.8%, P = 0.037, respectively). The requirement for β-receptor blockade was more frequent in the ICNBs group than in the PVB group (5.9 vs. 25%, P = 0.033).

Conclusion: After placement of the needle using ultrasound guidance, a single-shot thoracic PVB is a well tolerated and effective technique to reduce the incidences of postoperative SVT and atrial fibrillation in patients undergoing thoracoscopic pulmonary resection.

Trial registration: http://www.chictr.org/cn/, registration number: ChiCTR-IOR-17010952.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anesthetics, Local / administration & dosage
  • Atrial Fibrillation / diagnostic imaging*
  • Atrial Fibrillation / epidemiology*
  • Autonomic Nerve Block / adverse effects*
  • Autonomic Nerve Block / methods
  • Female
  • Humans
  • Incidence
  • Injections, Spinal / adverse effects*
  • Injections, Spinal / methods
  • Intercostal Nerves / diagnostic imaging*
  • Intercostal Nerves / drug effects
  • Male
  • Middle Aged
  • Thoracic Surgery, Video-Assisted / methods*
  • Thoracic Vertebrae / diagnostic imaging
  • Ultrasonography, Interventional / methods

Substances

  • Anesthetics, Local