Recent advances in functional nanostructures as cancer photothermal therapy

Int J Nanomedicine. 2018 May 17:13:2897-2906. doi: 10.2147/IJN.S161031. eCollection 2018.

Abstract

Being a non-invasive and relatively safe technique, photothermal therapy has attracted a lot of interest in the cancer treatment field. Recently, nanostructure technology has entered the forefront of cancer therapy owing to its ability to absorb near-infrared radiation as well as efficient light to heat conversion. In this study, key nanostructures for cancer therapy including gold nanoparticles, magnetite iron oxide nanoparticles, organic nanomaterials, and novel two-dimensional nanoagents such as MXenes are discussed. Furthermore, we briefly discuss the characteristics of the nanostructures of these photothermal nanomaterial agents, while focusing on how nanostructures hold potential as cancer therapies. Finally, this review offers promising insight into new cancer therapy approaches, particularly in vivo and in vitro cancer treatments.

Keywords: cancer therapy; nanostructures; near-infrared; photothermal therapy; plasmonic.

Publication types

  • Review

MeSH terms

  • Animals
  • Gold / chemistry
  • Humans
  • Hyperthermia, Induced / instrumentation
  • Hyperthermia, Induced / methods*
  • Infrared Rays
  • Magnetite Nanoparticles / therapeutic use
  • Nanostructures / chemistry*
  • Nanostructures / therapeutic use*
  • Neoplasms / therapy*
  • Phototherapy / instrumentation
  • Phototherapy / methods*

Substances

  • Magnetite Nanoparticles
  • Gold