Phage Therapy: What Have We Learned?

Viruses. 2018 May 28;10(6):288. doi: 10.3390/v10060288.

Abstract

In this article we explain how current events in the field of phage therapy may positively influence its future development. We discuss the shift in position of the authorities, academia, media, non-governmental organizations, regulatory agencies, patients, and doctors which could enable further advances in the research and application of the therapy. In addition, we discuss methods to obtain optimal phage preparations and suggest the potential of novel applications of phage therapy extending beyond its anti-bacterial action.

Keywords: anti-phage antibodies; experimental therapy; immunomodulation; phage cocktails; phage therapy; prophage.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Bacteria / virology
  • Bacteriophages
  • Clinical Trials as Topic
  • Humans
  • Immunomodulation
  • Mice
  • Phage Therapy / trends*
  • Prophages