Abnormalities of chromosomes 1 and 11 in Wilms' tumor

Cancer Genet Cytogenet. 1985 Jan 15;14(3-4):331-8. doi: 10.1016/0165-4608(85)90199-2.

Abstract

Cytogenetic studies were performed successfully on 14 cases of Wilms' tumor. Six cases had detectable rearrangements of 11p, and 7 cases had structural abnormalities of chromosome #1. Two cases with advanced stage disease showed multiple translocations, resulting in hypodiploidy with a normal DNA complement.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Child
  • Child, Preschool
  • Chromosome Aberrations*
  • Chromosome Banding
  • Chromosomes, Human, 1-3*
  • Chromosomes, Human, 6-12 and X*
  • Female
  • Humans
  • Infant
  • Karyotyping
  • Kidney Neoplasms / genetics*
  • Male
  • Translocation, Genetic
  • Wilms Tumor / genetics*