Abstract
Cytogenetic studies were performed successfully on 14 cases of Wilms' tumor. Six cases had detectable rearrangements of 11p, and 7 cases had structural abnormalities of chromosome #1. Two cases with advanced stage disease showed multiple translocations, resulting in hypodiploidy with a normal DNA complement.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Child
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Child, Preschool
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Chromosome Aberrations*
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Chromosome Banding
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Chromosomes, Human, 1-3*
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Chromosomes, Human, 6-12 and X*
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Female
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Humans
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Infant
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Karyotyping
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Kidney Neoplasms / genetics*
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Male
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Translocation, Genetic
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Wilms Tumor / genetics*