Exploring the role of defective fibronectin matrix assembly in the VHL-associated CNS hemangioblastoma

Drug Metab Pers Ther. 2018 Sep 25;33(3):127-134. doi: 10.1515/dmpt-2018-0007.
No abstract available

Keywords: CNS hemangioblastoma; VHL syndrome; cilengitide; fibronectin assembly.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Central Nervous System / metabolism*
  • Extracellular Matrix / metabolism
  • Fibronectins / genetics
  • Fibronectins / metabolism*
  • Hemangioblastoma / metabolism*
  • Humans
  • Kidney / metabolism
  • Mutation
  • Von Hippel-Lindau Tumor Suppressor Protein / genetics
  • Von Hippel-Lindau Tumor Suppressor Protein / metabolism*
  • von Hippel-Lindau Disease / metabolism*

Substances

  • Fibronectins
  • Von Hippel-Lindau Tumor Suppressor Protein
  • VHL protein, human