Objective: To review the progress of cell sheet technology and its application in bone and cartilage engineering.
Methods: The recent literature concerning the cell sheet technology used in treatment of bone and cartilage defects was extensively reviewed and summarized.
Results: Cell sheet built through many different ways can protect extracellular matrix from proteolytic enzymes. As a three-dimensional structure, cell sheet can repair bone and cartilige defects via folding, wrapping scaffold, or be created by the layering of individual cell sheets.
Conclusion: The cell sheet technology would have a very broad prospects in bone and cartilage tissue engineering in future.
目的: 对细胞膜片技术在骨与软骨组织工程修复领域的研究进展进行综述。.
方法: 广泛查阅近年应用细胞膜片技术进行骨与软骨修复重建的相关文献，归纳总结后进行综述。.
结果: 通过多种不同方法构建出的细胞膜片有效地保护了细胞外基质。细胞膜片通过自身折叠、包被相应生物材料以及不同膜片间叠加等方式，在骨与软骨组织修复中展现出了良好的修复效果。.
结论: 细胞膜片技术作为骨与软骨组织工程领域一种新的治疗策略具有广阔应用前景。.
Keywords: Cell sheet technology; bone tissue engineering; cartilage tissue engineering.