Objective:To investigate the related factors of mucosal melanoma of head and neck with lymph node metastasis for early diagnosis and further treatments. Method:A retrospective analysis of 117 cases of head and neck mucosal malignant melanoma patients which received surgical treatment was performed. Eleven cases of patients with pathologically confirmed lymph node metastasis and 33 cases without lymph node metastasis (1∶3) were randomly selected to analyze. The related factors of lymph node metastasis of head and neck mucosal melanoma patients including age, gender, whether the existence of recurrence, bone invasion, lesion location were analyzed. The single factor and logistic regression analysis were performed, P<0.05 difference was statistically significant. Result:The lymph node metastasis rate of head and neck mucosal melanoma was 9.40%(11/117), the single factor analysis showed that there were 3 factors to be associated with lymph node metastasis, which was recurrence (P=0.0000), bone invasion (P=0.001), primary position (P=0.007). Recurrence (P=0.021) was a risk factor for lymph node metastasis according to the Logistic regression analysis, and the impact of bone invasion (P=0.487) and primary location (P=0.367) remained to be further explored. Conclusion:The patients of head and neck mucosal melanoma with the presence of recurrent usually accompanied by a further progression of the disease, such as lymph node metastasis, so for recurrent patients should pay special attention to the situation of lymph node and choose the reasonable treatment.
Keywords: head and neck neoplasms; lymph metastasis; melanomay.
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