Response to Roberts et al. 2018: is breast cancer truly caused by MSH6 and PMS2 variants or is it simply due to a high prevalence of these variants in the population?

Genet Med. 2019 Jan;21(1):256-257. doi: 10.1038/s41436-018-0029-1. Epub 2018 May 24.

Authors

S W Ten Broeke¹, M Suerink², M Nielsen²

Affiliations

¹ Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands. tenbroeke@lumc.nl.
² Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.

PMID: 29795439
DOI: 10.1038/s41436-018-0029-1

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Breast Neoplasms
Colorectal Neoplasms, Hereditary Nonpolyposis*
Humans
Mismatch Repair Endonuclease PMS2*
MutS Homolog 2 Protein
Prevalence

Substances

PMS2 protein, human
Mismatch Repair Endonuclease PMS2
MutS Homolog 2 Protein