Towards personalized medicine: exploring the consequences of the effect model-based approach

Per Med. 2011 Sep;8(5):581-586. doi: 10.2217/pme.11.54.

Abstract

Although personalized medicine has been a subject of research and debate in recent years, it has been underused in medical practice, except in some cancers. We believe that the main reason for the gap between the potential of personalized medicine and its use in daily medical practice can be explained by the lack of an appropriate tool to facilitate the use of biomarker values in a doctor's decision-making process. We propose that the effect model could form the basis of such a tool.

Keywords: decision making; effect model; mathematical model; personalized medicine; risk assessment.