Atria Depolarization in Rats with Alcoholic Cardiomyopathy

Dokl Biol Sci. 2018 Mar;479(1):41-43. doi: 10.1134/S0012496618020035. Epub 2018 May 22.

Abstract

Chronotopography of atrial subepicardium depolarization has been studied in a rat model of alcoholic cardiomyopathy. Formation of independent sources of initial atrial activity has been detected in the right and left atria. These sources induced the formation of several depolarization fronts that propagated autonomously, and this can be regarded as the cause of atrial arrhythmia.

MeSH terms

  • Action Potentials
  • Animals
  • Cardiomyopathy, Alcoholic / physiopathology*
  • Heart Atria / physiopathology*
  • Heart Rate
  • Male
  • Rats