Optical coherence tomography in STEMI with bioresorbable scaffold: possible cause of coronary flow impairment? A sub-study from the Prague 19 trial

Heart Vessels. 2018 Nov;33(11):1282-1287. doi: 10.1007/s00380-018-1184-7. Epub 2018 May 18.

Abstract

This study assessed the Optical Coherence Tomography (OCT) impact on the coronary flow in ST-elevation myocardial infarction (STEMI) after bioresorbable scaffold implantation. Only few data about OCT use in STEMI are available and coronary flow before and after OCT is not well studied yet. 54 patients with OCT performed at the end of procedure from the Prague 19 trial were selected and coronary flow was evaluated as TIMI frame count (TFC) before and just after OCT. Significant increase in TIMI frame count after OCT [from 9.5 (6.75-12.25) to 11.5 (8-15.25) frames; p = 0.001] and high verapamil administration (18%) was reported. OCT at the end of primary percutaneous coronary intervention with bioresorbable scaffold is a feasible procedure. However, it seems to be associated with flow deterioration.

Keywords: Bioabsorbable scaffold; Coronary blood flow; Optical coherence tomography; STEMI.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Absorbable Implants*
  • Coronary Angiography
  • Coronary Circulation / physiology*
  • Coronary Vessels / diagnostic imaging*
  • Coronary Vessels / surgery
  • Drug-Eluting Stents
  • Everolimus / pharmacology
  • Female
  • Humans
  • Male
  • Percutaneous Coronary Intervention
  • Prospective Studies
  • Prosthesis Design
  • Regional Blood Flow / physiology*
  • ST Elevation Myocardial Infarction / diagnosis
  • ST Elevation Myocardial Infarction / physiopathology
  • ST Elevation Myocardial Infarction / surgery*
  • Time Factors
  • Tissue Scaffolds*
  • Tomography, Optical Coherence / methods*
  • Treatment Outcome

Substances

  • Everolimus