Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts

BMC Res Notes. 2018 May 18;11(1):318. doi: 10.1186/s13104-018-3405-7.

Abstract

Objective: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them.

Results: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-third of them were from infants between 2 and 3 months old. The most common symptoms were paroxysms of coughing (88.9%), difficulty breathing (72.2%), cyanosis (77.8%) and fever (50%). The mother was the most common symptomatic carrier (27.8%), followed by uncles/aunts (22.2%) among children with pertussis.

Keywords: Bordetella pertussis; PCR; Pertussis; Peru; Whooping cough.

MeSH terms

  • Bordetella pertussis / isolation & purification*
  • Bordetella pertussis / pathogenicity
  • Child, Preschool
  • Female
  • Hospitals / statistics & numerical data*
  • Humans
  • Infant
  • Male
  • Peru / epidemiology
  • Polymerase Chain Reaction
  • Whooping Cough* / diagnosis
  • Whooping Cough* / epidemiology
  • Whooping Cough* / microbiology