Extremely halophilic pleomorphic archaeal virus HRPV9 extends the diversity of pleolipoviruses with integrases

Nina S Atanasova; Tatiana A Demina; Sudar N V Krishnam Rajan Shanthi; Hanna M Oksanen; Dennis H Bamford

doi:10.1016/j.resmic.2018.04.004

Extremely halophilic pleomorphic archaeal virus HRPV9 extends the diversity of pleolipoviruses with integrases

Res Microbiol. 2018 Nov;169(9):500-504. doi: 10.1016/j.resmic.2018.04.004. Epub 2018 May 14.

Authors

Nina S Atanasova¹, Tatiana A Demina², Sudar N V Krishnam Rajan Shanthi³, Hanna M Oksanen⁴, Dennis H Bamford⁵

Affiliations

¹ Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Viikinkaari 9B, FI-00014, Helsinki, Finland; Finnish Meteorological Institute, Erik Palménin aukio 1, FI-00560, Helsinki, Finland. Electronic address: nina.atanasova@helsinki.fi.
² Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Viikinkaari 9B, FI-00014, Helsinki, Finland. Electronic address: tatiana.demina@helsinki.fi.
³ Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Viikinkaari 9B, FI-00014, Helsinki, Finland. Electronic address: rajansudar@gmail.com.
⁴ Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Viikinkaari 9B, FI-00014, Helsinki, Finland. Electronic address: hanna.oksanen@helsinki.fi.
⁵ Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Viikinkaari 9B, FI-00014, Helsinki, Finland. Electronic address: dennis.bamford@helsinki.fi.

PMID: 29772256
DOI: 10.1016/j.resmic.2018.04.004

Abstract

Certain pleomorphic archaeal viruses are highly infectious even at saturated salt. These viruses belong to the genus Betapleolipovirus of the recently described archaeal virus family Pleolipoviridae. Pleolipoviruses comprise single-stranded or double-stranded, circular or linear DNA genomes that share countless homologues among various archaeal genetic elements. Here we describe a new extremely halophilic betapleolipovirus, Halorubrum pleomorphic virus 9 (HRPV9), which has an integrase gene. We also identified new genes encoding minor pleolipoviral structural proteins. The studies on HRPV9 enhance our knowledge on pleolipoviruses, especially their reciprocal relatedness and relation to certain archaeal plasmids, proviruses and membrane vesicles.

Keywords: Archaeal virus; Halophilic; Hypersaline environment; Pleomorphic virus.

MeSH terms

Archaeal Viruses / classification
Archaeal Viruses / enzymology*
Archaeal Viruses / genetics*
Archaeal Viruses / physiology
DNA Viruses / genetics
DNA, Viral / genetics
Genome, Viral
Integrases / genetics*
Open Reading Frames
Plasmids
Salinity*
Virion

Substances

DNA, Viral
Integrases