Phenolic Profile of Artemisia alba Turra

Chem Biodivers. 2018 Jul;15(7):e1800109. doi: 10.1002/cbdv.201800109. Epub 2018 Jun 11.

Abstract

The aim of this study was to evaluate flower and leaf methanol extracts of Artemisia alba Turra for their total phenolic and flavonoid contents, antioxidant capacity and to investigate their phenolic composition. The flower extract was richer in total phenolics and flavonoids and possessed higher antioxidant activity through DPPH and ABTS assays. The UHPLC-PDA-MS analysis of the flower and leaf methanol extracts revealed similar phenolic profile and allowed identification of 31 phenolic compounds (flavonoids, coumarins, and phenolic acids) by comparison with the respective reference compounds or tentatively characterized by their chromatographic behavior, UV patterns, and MS fragmentations. The presence of hispidulin, jaceosidin, desmethoxycentaureidin, and dicaffeoyl esters of quinic acid in A. alba is reported herein for the first time. The distribution of flavonoids in A. alba from different origins was discussed from chemotaxonomic point of view.

Keywords: Artemisia alba Turra; UHPLC-PDA-MS; antioxidant activity; flavonoids; phenolic compounds.

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology*
  • Artemisia / chemistry*
  • Benzothiazoles / antagonists & inhibitors
  • Biphenyl Compounds / antagonists & inhibitors
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification
  • Flavonoids / pharmacology
  • Flowers / chemistry*
  • Molecular Structure
  • Phenols / chemistry
  • Phenols / isolation & purification
  • Phenols / pharmacology*
  • Picrates / antagonists & inhibitors
  • Plant Leaves / chemistry*
  • Sulfonic Acids / antagonists & inhibitors

Substances

  • Antioxidants
  • Benzothiazoles
  • Biphenyl Compounds
  • Flavonoids
  • Phenols
  • Picrates
  • Sulfonic Acids
  • 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid
  • 1,1-diphenyl-2-picrylhydrazyl