Case Report: Haemolytic anaemia with ceftazidime use in a patient with cystic fibrosis

Jun Yong; Freddy Frost; Dilip Nazareth; Martin Walshaw

doi:10.12688/f1000research.14505.1

Case Report: Haemolytic anaemia with ceftazidime use in a patient with cystic fibrosis

F1000Res. 2018 Apr 18:7:475. doi: 10.12688/f1000research.14505.1. eCollection 2018.

Authors

Jun Yong¹, Freddy Frost¹, Dilip Nazareth¹, Martin Walshaw¹

Affiliation

¹ Liverpool Heart and Chest Hospital NHS Trust, Liverpool, L14 3PE, UK.

Abstract

Drug-induced Immune Haemolytic Anaemia (DIIHA) is a rare but serious complication of cephalosporin use. Ceftazidime is recognized to be a rare cause of DIIHA. We report and discuss a case of DIIHA in a person with cystic fibrosis who developed severe haemolytic anaemia following use of ceftazidime in the management of an acute pseudomonal pulmonary exacerbation.

Keywords: Ceftazidime; Cephalosporins; Drug Induced Immune Haemolytic Anaemia.

Grants and funding

The author(s) declared that no grants were involved in supporting this work.