Age-gender distribution of coronary artery calcium score in a black African population in Ghana

Vasc Health Risk Manag. 2018 May 4:14:75-80. doi: 10.2147/VHRM.S160669. eCollection 2018.

Abstract

Background: Distribution of coronary artery calcium (CAC) has been determined in different heterogeneous populations in the Multi-Ethnic Study of Atherosclerosis (MESA). Based on findings showing that geography and culture can influence CAC scoring beyond traditional race groups, we determined the distribution of CAC in a homogenous black African population to provide an initial basis for a larger CAC score study in Africa.

Methods and results: This is a preliminary study using computed tomography to determine the CAC scores within a black African population who were referred to our center. Other information on patients were recorded through a combination of one-on-one interviews and medical records. A total of 170 patients were involved in our study, including 60.6% males, with an average age of 53.9 ± 9.2 years. The majority (78.8%) had a zero calcium score, with patients within the age group of 55-64 years dominating the non-zero calcium score population. Males were found to have higher calcium levels compared to females, and coronary artery calcification and prevalence steadily rose with the increasing age. However, P-values of 0.328 and <0.001 were observed with distribution of CAC according to gender and age, respectively.

Conclusion: Findings from this study showed that the distribution of CAC was markedly affected by the age of our study population, which will be more apparent in a larger study.

Keywords: calcium score; computed tomography; coronary artery calcium; coronary artery disease.

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Black People*
  • Comorbidity
  • Computed Tomography Angiography
  • Coronary Angiography / methods
  • Coronary Artery Disease / diagnostic imaging
  • Coronary Artery Disease / ethnology*
  • Female
  • Ghana / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Multidetector Computed Tomography
  • Preliminary Data
  • Prevalence
  • Risk Factors
  • Severity of Illness Index
  • Sex Distribution
  • Vascular Calcification / diagnostic imaging
  • Vascular Calcification / ethnology*