Circulating nucleosomes: a new addition to the personalized medicine toolkit

Per Med. 2014 Aug;11(6):565-568. doi: 10.2217/pme.14.47.

Abstract

Dr Stefan Holdenrieder is senior physician at the Institute of Clinical Chemistry and Clinical Pharmacology of the University Hospital Bonn, Germany. He is an expert in the field of circulating tumor biomarkers and particularly circulating nucleosomes. He has conducted numerous clinical studies concerning the biomarker-based detection and monitoring of cancer diseases and has published more than 90 papers in recognized international journals.

Keywords: biomarkers; blood-based diagnostic; circulating nucleosomes; histones; oncology; therapy response.