Abstract
Three new triterpenoid saponins, julibrosides A5-A7 (1-3), together with five known saponins (4-8), were isolated from the stem bark of Albizia julibrissin. Their structures were elucidated on the basis of extensive spectroscopic data analysis of MS, 1D and 2D NMR, and chemical methods. Compounds 7 and 8 were isolated from the genus Albizia for the first time. The new compounds showed no cytotoxicity and anti-inflammatory activity.
Keywords:
Leguminosae; julibrosides A–A; triterpenoid saponin.
MeSH terms
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Albizzia / chemistry*
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Animals
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Anti-Inflammatory Agents, Non-Steroidal / pharmacology
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Antineoplastic Agents, Phytogenic / pharmacology
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Cell Line, Tumor
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Humans
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Magnetic Resonance Spectroscopy
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Mass Spectrometry
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Mice
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Molecular Structure
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Negative Results
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Nitric Oxide / metabolism
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Plant Bark / chemistry
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Plant Stems / chemistry
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Saponins / chemistry*
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Saponins / pharmacology
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Triterpenes / chemistry*
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Triterpenes / pharmacology
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Antineoplastic Agents, Phytogenic
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Saponins
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Triterpenes
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Nitric Oxide