Predictors of a drainable suppurative adenitis among children presenting with cervical adenopathy

Am J Emerg Med. 2019 Jan;37(1):109-113. doi: 10.1016/j.ajem.2018.05.004. Epub 2018 May 5.

Abstract

Objectives: We sought to identify predictors for a drainable suppurative adenitis [DSA] among patients presenting with acute cervical lymphadenitis.

Methods: A retrospective cross sectional study of all patients admitted to an urban pediatric tertiary care emergency department over a 15 year period. Otherwise healthy patients who underwent imaging for an evaluation of cervical lymphadenitis were included. Cases were identified using a text-search module followed by manual review. We excluded immunocompromised patients and those with lymphadenopathy felt to be not directly infected (i.e. reactive) or that was not acute (symptom duration >28 days). Data collected included: age, gender, duration of symptoms, highest recorded temperature, physical exam findings, laboratory and imaging results, and surgical findings. A DSA was defined as >1.5 cm in diameter on imaging. We performed binary logistic regression to determine independent clinical predictors of a DSA.

Results: Three hundred sixty-one patients met inclusion criteria. Three hundred six patients (85%) had a CT scan, 55 (15%) had an ultrasound and 33 (9%) had both. DSA was identified in 71 (20%) patients. Clinical features independently associated with a DSA included absence of clinical pharyngitis, WBC >15,000/mm3, age ≤3 years, anterior cervical chain location, largest palpable diameter on exam >3 cm and prior antibiotic treatment of >24 h. The presence of fever, skin erythema, or fluctuance on examination, was not found to be predictive of DSA.

Conclusions: We identified independent predictors of DSA among children presenting with cervical adenitis. Risk can be stratified into risk groups based on these clinical features.

Keywords: Adenitis; Adenopathy; Cervical; Suppurative.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Drainage / methods*
  • Emergency Medical Services*
  • Female
  • Humans
  • Lymphadenitis / diagnosis*
  • Lymphadenitis / therapy
  • Male
  • Pharyngitis / diagnosis*
  • Pharyngitis / therapy
  • Retrospective Studies
  • Suppuration
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Ultrasonography

Substances

  • Anti-Bacterial Agents