Automated Visualization of Genetic Designs Using DNAplotlib

Methods Mol Biol. 2018:1772:399-409. doi: 10.1007/978-1-4939-7795-6_22.

Abstract

Visualization of complex genetic systems can help efficiently communicate important design features and clearly illustrate overall structures. To aid in the creation of such diagrams, standards such as the Synthetic Biology Open Language Visual (SBOLv) have been established to ensure that specific symbols and shapes convey the same meaning for genetic parts across the field. Here, we describe several ways that the computational tool DNAplotlib can be used to automate the generation of SBOLv standard-compliant diagrams covering simple genetic designs to large libraries of genetic constructs.

Keywords: Genetic design; SBOLv; Standardization; Synthetic biology; Systems biology; Visualization.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computers
  • DNA / genetics*
  • Genetic Therapy / methods
  • Software
  • Synthetic Biology / methods*

Substances

  • DNA