Applications of proteomics in pharmaceutical research and development

Biochim Biophys Acta Proteins Proteom. 2019 Jan;1867(1):17-21. doi: 10.1016/j.bbapap.2018.05.008. Epub 2018 May 9.

Abstract

The significance of proteomics in the pharmaceutical industry has increased since overcoming initial difficulties. This review discusses recent proteomics publications from pharmaceutical companies to identify new trends in proteomics applications to research and development. Applications of proteomics such as chemical proteomics, protein expression profiling, targeted protein quantitation, analysis of protein-protein interactions and post-translational modification are widely used by various sections of the industry. Technological advancements in proteomics will further accelerate pharmaceutical research and development.

Keywords: Chemical proteomics; Drug discovery; Pharmaceutical; Post-translational modification; Proteome; Proteomics.

Publication types

  • Review

MeSH terms

  • Animals
  • Drug Discovery / methods
  • Drug Discovery / trends
  • Humans
  • Pharmaceutical Research / methods*
  • Pharmaceutical Research / trends*
  • Protein Processing, Post-Translational
  • Proteomics / methods*
  • Proteomics / trends
  • Transcriptome / genetics