[A new lignan from rhizome of Stellera chamaejasme]

Shu-Na Liu; Jun He; Xiao-Xue Wang; Bing-Zhi Ma; Wei-Ku Zhang; Jie-Kun Xu

doi:10.19540/j.cnki.cjcmm.20180116.003

[A new lignan from rhizome of Stellera chamaejasme]

Zhongguo Zhong Yao Za Zhi. 2018 Apr;43(8):1649-1653. doi: 10.19540/j.cnki.cjcmm.20180116.003.

[Article in Chinese]

Authors

Shu-Na Liu^{1

2}, Jun He³, Xiao-Xue Wang³, Bing-Zhi Ma³, Wei-Ku Zhang², Jie-Kun Xu¹

Affiliations

¹ School of Life Sciences & School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
² Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China.
³ Department of Pharmacy, China-Japan Friendship Hospital, Beijing 100029, China.

PMID: 29751712
DOI: 10.19540/j.cnki.cjcmm.20180116.003

Abstract

To investigate the chemical compounds from the rhizome of Stellera chamaejasme, nine lignans, including stellerachamin A (1), 8-hydroxypluviatolide (2), wikstromol (3), pinoresinol (4), matairesinol (5), dextrobursehernin (6), hinokinin(7), (-)-glaberide I (8) and （-） medioresinol (9) were isolated by various chromatographic methods. Their structures were extensively determined on basis of MS and NMR spectroscopic data analysis. Among them, compound 1 was a new lignan, and compounds 2 and 7 were isolated from Thymelaeaceae for the first time.

Keywords: Stellera chamaejasme; stellerachamin A; structural identification.

MeSH terms

Lignans
Molecular Structure
Rhizome
Thymelaeaceae*

Substances

Lignans