The overarching framework of translation and integration into healthcare: a case for the LAL model

Per Med. 2014 Jan;11(1):41-62. doi: 10.2217/pme.13.97.

Abstract

Background: Recently, there has been a substantial increase in relevant genome-based technologies into market. Compared with its utilization in healthcare systems, we notice a huge gap. In order to address this bottleneck, we previously developed the Learning-Adapting-Leveling (LAL) model.

Aim: In this article, we aim to demonstrate the overarching reach of the model for translation to market and implementation into healthcare systems moving towards personalized healthcare.

Methods: We use qualitative logical reasoning with the LAL model as a reference.

Results: We found that technology transfer, health needs assessment, health technology assessment and health impact assessment are justified for their inclusion. In addition, the public health wheel is justified as a good reference frame along with value of information.

Conclusion: We conclude that as the LAL model covers all dimensions and tools for translation and implementation in a defined method; it can therefore be considered as the overarching framework for translation and implementation into healthcare.

Keywords: ACCE/EGAPP; Learning-Adapting-Leveling model; Public Health Genomics; health impact assessment; health needs assessment; health technology assessment; personalized healthcare; public health wheel; technology transfer; translational research.