Ethical considerations in the implementation of nutrigenetics/nutrigenomics

Per Med. 2017 Jan;14(1):75-83. doi: 10.2217/pme-2016-0035. Epub 2016 Nov 30.

Abstract

Awareness of ethical issues that may be raised by the implementation of nutrigenetic/nutrigenomic (NGx) testing and personalized nutrition, at an individual or a public health level, is crucial to ensure the latter's sound and effective implementation. NGx tests that are currently offered or developed have different natures and scopes. We provide an example of NGx testing on the MTHFR gene to illustrate the current challenges when it comes to grasp the meaning of the results of such testing. In addition, NGx testing is developed within an evolving landscape of new genomic technologies and occurs at a time when public health policies mainly focus on preventive and predictive healthcare, with an emphasis on increased individual responsibility. The ethical issues raised by such a context and the genetic nature of NGx testing both should be carefully evaluated.

Keywords: ethics; nutrigenetics; nutrigenomics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genetic Testing / methods
  • Genomics
  • Humans
  • Methylenetetrahydrofolate Reductase (NADPH2) / genetics
  • Methylenetetrahydrofolate Reductase (NADPH2) / metabolism
  • Nutrigenomics / ethics*
  • Nutrition Policy
  • Nutritional Status
  • Precision Medicine / ethics*
  • Predictive Value of Tests
  • Public Health

Substances

  • MTHFR protein, human
  • Methylenetetrahydrofolate Reductase (NADPH2)

Grants and funding