Toxicological Aspect of Some Selected Medicinal Plant Samples Collected from Djelfa, Algeria Region

Biol Trace Elem Res. 2019 Jan;187(1):301-306. doi: 10.1007/s12011-018-1365-3. Epub 2018 May 10.

Abstract

Instrumental neutron activation analysis (INAA) has been used to determine the concentration of some toxic chemical elements in a variety of aromatic plants samples collected from Djelfa region. In the present work, eight medicinal plants were examined, such as Artemisia herba-alba Asso., Artemisia compestris L., Laurus nobilis L., Origanum vulgare L., Mentha spicata L., Rosmarinus officinalis L., Mentha pulegium L., and Pistacia lentiscus L. The levels of toxic elements were compared to their daily total intake; Arsenic was present in all plant species examined, with a concentration ranging from 0.18 to 5.44 μg g- 1. Bromine was also detected in all the medicinal plant species, with high concentrations, compared to arsenic except in the case of Laurus nobilis that has the highest concentration of arsenic. Cerium, cobalt, chromium, and antimony were presented in all plant species. The exactitude of the results was assessed by analyzing the certified reference material of SRM-NIST 1573a and CRM GB07605 (GSV4). These data analysis for this medicinal plant can be useful for therapeutics and pharmaceutical purposes.

Keywords: Antimony; Arsenic; Bromine; Daily total intake; INAA method; Medicinal plants; Toxic elements.

MeSH terms

  • Algeria
  • Antimony / analysis*
  • Antimony / toxicity
  • Arsenic / analysis*
  • Arsenic / toxicity
  • Bromine / analysis*
  • Bromine / toxicity
  • Cerium / analysis*
  • Cerium / toxicity
  • Chromium / analysis*
  • Chromium / toxicity
  • Cobalt / analysis*
  • Cobalt / toxicity
  • Plants, Medicinal / chemistry*
  • Plants, Medicinal / toxicity*

Substances

  • Chromium
  • Cerium
  • Cobalt
  • Antimony
  • Arsenic
  • Bromine