Opioid Use Disorders and Pregnancy

Amanda J Johnson; Cresta W Jones

doi:10.1016/j.ogc.2018.01.008

Opioid Use Disorders and Pregnancy

Obstet Gynecol Clin North Am. 2018 Jun;45(2):201-216. doi: 10.1016/j.ogc.2018.01.008. Epub 2018 Mar 15.

Authors

Amanda J Johnson¹, Cresta W Jones²

Affiliations

¹ Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
² Department of Obstetrics, Gynecology and Women's Health, Division of Maternal-Fetal Medicine, University of Minnesota Medical School, 606 24th Avenue S, Suite 400, Minneapolis, MN 55455, USA. Electronic address: jonesc@umn.edu.

PMID: 29747726
DOI: 10.1016/j.ogc.2018.01.008

Abstract

Opioid use disorder presents an increased risk of complications in pregnancy, particularly when untreated. To optimize outcomes, medication-assisted treatment using methadone or buprenorphine as a part of a comprehensive care model is recommended. Neonatal abstinence syndrome and poor fetal growth remain significant complications of this disorder despite maternal treatment.

Keywords: Buprenorphine; Methadone; Neonatal abstinence syndrome; Opioid use disorder; Pregnancy.

Publication types

Review

MeSH terms

Female
Humans
Infant, Newborn
Maternal Health Services
Neonatal Abstinence Syndrome / etiology
Opioid-Related Disorders / complications
Opioid-Related Disorders / therapy*
Pregnancy
Pregnancy Complications / therapy*