Hemorrhagic bullous lesions in Henoch-Schönlein purpura: a case report and review of the literature

BMC Pediatr. 2018 May 10;18(1):157. doi: 10.1186/s12887-018-1117-8.

Abstract

Background: Henoch-Schönlein purpura (HSP) is a common vasculitis in childhood characterized by purpura, arthritis, abdominal pain and renal involvement. However, bullous HSP is a rare cutaneous manifestation, and a few cases have been reported.

Case presentation: Herein, we report a 15-year-old male with bullous HSP who presented with severe abdominal pain and hemorrhagic bullous lesions over his lower extremities. He was treated with corticosteroid, after which the symptoms improved dramatically. No recurrence was noted after follow-up, though scarring was present. We also reviewed the literature related to bullous HSP and identified 39 cases, most of whom were treated with corticosteroids.

Conclusion: Clinicians should be aware of the atypical types of HSP, including bullous HSP. Most patients with bullous HSP have a good prognosis.

Keywords: Case report; Hemorrhagic bullae; Henoch-Schönlein purpura; Leukocytoclastic vasculitis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abdominal Pain / etiology
  • Abdominal Pain / pathology
  • Adolescent
  • Anti-Inflammatory Agents / therapeutic use
  • Blister / etiology*
  • Glucocorticoids / therapeutic use
  • Hemorrhage / etiology*
  • Hemorrhage / pathology
  • Humans
  • Hydrocortisone / therapeutic use
  • IgA Vasculitis / complications*
  • IgA Vasculitis / drug therapy
  • IgA Vasculitis / pathology
  • Lower Extremity / pathology
  • Male
  • Prednisolone / therapeutic use

Substances

  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Prednisolone
  • Hydrocortisone