[Mitomycin C HIVEC. Update and results in high risk patients]

Arch Esp Urol. 2018 May;71(4):417-425.
[Article in Spanish]

Abstract

Adjuvant endovesical treatment is a research field in constant exploration with the aim to minimize the risk of recurrence and progression of non muscle invasive bladder tumors. Over the last years, the administration of chemotherapy in a chemo hyperthermia regimen has been added to the existing regimens. There are various systems for its administration, but this article focus on HIVEC (Hyperthermic IntraVEsical Chemotherapy) and its current status. In this review article we update the results of this system in the case-scenarios it has been used (preoperative with ablative intention and as adjuvant therapy with prophylactic purposes), tolerance and security issues, on-going clinical trials and future perspectives.

Publication types

  • Review

MeSH terms

  • Antibiotics, Antineoplastic / therapeutic use*
  • Combined Modality Therapy
  • Humans
  • Hyperthermia, Induced*
  • Mitomycin / therapeutic use*
  • Risk Factors
  • Urinary Bladder Neoplasms / therapy*

Substances

  • Antibiotics, Antineoplastic
  • Mitomycin