Eversion endarterectomy of the deceased donor renal artery to prevent kidney discard

Clin Transplant. 2018 Jun;32(6):e13275. doi: 10.1111/ctr.13275. Epub 2018 Jun 19.

Abstract

Introduction: Deceased donor (DD) kidneys exhibiting severe atherosclerosis involving the renal artery (RA) may represent a contraindication to kidney transplantation (KT).

Methods: Eversion endarterectomy (EE) was performed as a salvage procedure to permit KT.

Results: We identified 17 cases (1.2% of all DD KTs during the study period) involving EE of the DD RA. Thirteen (76.5%) kidneys were imported, and mean Kidney Donor Profile Index (KDPI) was 81%. Mean DD age was 59 years, mean RA plaque length was 1.7 cm, and mean glomerulosclerosis on biopsy was 10%. Mean recipient age was 64 years, and dialysis vintage was 32 months. With a mean follow-up of 36 months, actual patient and graft survival rates were both 76.5%. One patient died early without a technical problem. Of the remaining 16 patients, 2-year patient and graft survival rates were both 100%. There were no early or late vascular complications. The incidence of delayed graft function was 35%. Mean serum creatinine and GFR levels in patients with functioning grafts at latest follow-up were 1.8 mg/dL and 40 mL/min, respectively.

Conclusions: EE appears to be a safe and under-utilized procedure that may prevent discard of marginal donor kidneys and is associated with acceptable short-term outcomes.

Keywords: deceased donor; eversion endarterectomy; expanded criteria donors; import kidneys; kidney discard; renal atherosclerosis.

MeSH terms

  • Cadaver
  • Delayed Graft Function / epidemiology
  • Endarterectomy / mortality*
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation / mortality*
  • Male
  • Middle Aged
  • North Carolina / epidemiology
  • Patient Selection
  • Prognosis
  • Prospective Studies
  • Renal Artery / surgery*
  • Retrospective Studies
  • Tissue Donors*
  • Tissue and Organ Procurement / methods*