Cardiac MRI for the evaluation of oncologic cardiotoxicity

J Nucl Cardiol. 2018 Dec;25(6):2148-2158. doi: 10.1007/s12350-018-1293-9. Epub 2018 May 7.

Abstract

Cancer therapeutics-related cardiac dysfunction (CTRCD) is a well-established adverse effect resulting from a number of cancer therapeutics. Newer immunotherapy has been associated with cardiomyopathy and myocarditis making comprehensive imaging useful for early recognition. Cardiac MRI (CMR) offers a comprehensive evaluation to detect CTRCD. Established guidelines for monitoring left ventricular ejection fraction for potential cardiotoxicity have recently incorporated CMR. We will review the utility of CMR in contemporary evaluation for potential oncologic cardiotoxicity.

Keywords: Cardiac MRI; cardiac toxicity; cardio-oncology.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Antineoplastic Agents / adverse effects*
  • Cardiotoxicity / diagnostic imaging*
  • Cicatrix / diagnostic imaging
  • Heart / diagnostic imaging*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Radiotherapy / adverse effects
  • Systole / physiology
  • Ventricular Dysfunction, Left / diagnostic imaging
  • Ventricular Function, Left

Substances

  • Antineoplastic Agents