Blackleg in cattle: Current understanding and future research perspectives- A review

M A Idrees; M Younus; S H Farooqi; A U Khan

doi:10.1016/j.micpath.2018.04.047

Blackleg in cattle: Current understanding and future research perspectives- A review

Microb Pathog. 2018 Jul:120:176-180. doi: 10.1016/j.micpath.2018.04.047. Epub 2018 May 4.

Authors

M A Idrees¹, M Younus², S H Farooqi³, A U Khan⁴

Affiliations

¹ Department of Pathobiology, KBCMA, College of Veterinary and Animal Sciences, 51600, Narowal, Pakistan.
² Department of Clinical Studies, KBCMA, College of Veterinary and Animal Sciences, 51600, Narowal, Pakistan.
³ Department of Clinical Studies, KBCMA, College of Veterinary and Animal Sciences, 51600, Narowal, Pakistan. Electronic address: shahid.hussain@uvas.edu.pk.
⁴ Department of Pathobiology, College of Veterinary and Animal Sciences, 35200, Jhang, Pakistan.

PMID: 29733903
DOI: 10.1016/j.micpath.2018.04.047

Abstract

Blackleg is an endogenous acute infection that principally affects cattle. The disease is caused by Clostridium chauvoei (C. chauvoei), an anaerobic spore forming bacterium. Control of this disease is based on stringent husbandry measures and scheduled vaccination plan. In recent years, the major virulence factors of C. chauvoei have been discovered and described. However, the pathogenesis of blackleg in cattle and in particular, circulation of the pathogen from point of entry to target tissues is yet not fully elucidated. This review summarizes the latest review of literature that significantly contributed for understanding the disease in cattle, and provides a foundation to preventive strategies.

Keywords: Cattle; Clostridium chauvoei; Pathogenesis; Virulence factors.

Publication types

Review
Retracted Publication