Highlighting IR Spectrochemical Imaging of the Retina

Ebrahim Aboualizadeh; Carol J Hirschmugl

doi:10.1016/j.tibs.2018.04.005

Highlighting IR Spectrochemical Imaging of the Retina

Trends Biochem Sci. 2018 Sep;43(9):650-653. doi: 10.1016/j.tibs.2018.04.005. Epub 2018 May 2.

Authors

Ebrahim Aboualizadeh¹, Carol J Hirschmugl²

Affiliations

¹ Center for Visual Science, University of Rochester, Rochester, NY, USA. Electronic address: eabouali@ur.rochester.edu.
² Department of Physics, University of Wisconsin-Milwaukee, Milwaukee, WI, USA; McPherson Eye Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. Electronic address: cjhirsch@uwm.edu.

PMID: 29729937
DOI: 10.1016/j.tibs.2018.04.005

Abstract

An emerging application of mid-IR spectrochemical imaging of the retina is its utility in studying the highly localized biomolecular alterations in the chemistry of retinal cell layers associated with several pathological conditions. Spatially resolved IR images highlight simultaneous chemical composition of the entire span of the retina in a label-free manner.

Published by Elsevier Ltd.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Animals
Diagnostic Imaging / methods*
Humans
Infrared Rays*
Retina / diagnostic imaging*
Retina / metabolism*
Spectrophotometry, Infrared