Pain Syndromes and Management in Adult Hematopoietic Stem Cell Transplantation

Joseph D Ma; Areej R El-Jawahri; Thomas W LeBlanc; Eric J Roeland

doi:10.1016/j.hoc.2018.01.012

Pain Syndromes and Management in Adult Hematopoietic Stem Cell Transplantation

Hematol Oncol Clin North Am. 2018 Jun;32(3):551-567. doi: 10.1016/j.hoc.2018.01.012. Epub 2018 Mar 9.

Authors

Joseph D Ma¹, Areej R El-Jawahri², Thomas W LeBlanc³, Eric J Roeland⁴

Affiliations

¹ Division of Clinical Pharmacy, UC San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, 9500 Gilman Drive, MC 0714, La Jolla, CA 92093-0714, USA. Electronic address: jdma@ucsd.edu.
² Division of Hematology/Oncology, Bone Marrow Transplant, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
³ Division of Hematologic Malignancies and Cellular Therapy, Duke University School of Medicine, 2424 Erwin Road, Suite 602, Durham, NC 27705, USA.
⁴ Department of Medicine, UC San Diego Moores Cancer Center, 3855 Health Sciences Drive, MC 0987, La Jolla, CA 92130, USA.

PMID: 29729788
DOI: 10.1016/j.hoc.2018.01.012

Abstract

Pain is a significant physical symptom that can be observed across the spectrum of hematopoietic stem cell transplant (HSCT) care. Pain assessment should include evaluation of the physical and functional components of pain. Management varies based on the type of HSCT-specific pain syndrome. Future directions for management of pain syndromes include the early integration of palliative care. The purpose of this review is to summarize various pain syndromes and management approaches in adult HSCT patients.

Keywords: Hematopoietic stem cell transplant; Neuropathy; Opioids; Pain.

Publication types

Review

MeSH terms

Adult
Hematopoietic Stem Cell Transplantation*
Humans
Pain Management / methods*
Pain* / etiology
Pain* / physiopathology
Peripheral Nervous System Diseases* / chemically induced
Peripheral Nervous System Diseases* / physiopathology
Peripheral Nervous System Diseases* / therapy
Syndrome