Screening for Wiskott-Aldrich syndrome by flow cytometry

Samuel C C Chiang; Sue M Vergamini; Ammar Husami; Lisa Neumeier; Kathryn Quinn; Teresa Ellerhorst; Linda Sheppard; Carrie Gifford; David Buchbinder; Avni Joshi; Marianne Ifversen; Gary I Kleiner; James B Bussel; Shanmuganathan Chandrakasan; Robert D Pesek; Tamara C Pozos; Melissa J Rose; Amy M Scurlock; Kejian Zhang; Yenan T Bryceson; Jack Bleesing; Rebecca A Marsh

doi:10.1016/j.jaci.2018.04.017

Screening for Wiskott-Aldrich syndrome by flow cytometry

J Allergy Clin Immunol. 2018 Jul;142(1):333-335.e8. doi: 10.1016/j.jaci.2018.04.017. Epub 2018 May 3.

Authors

Samuel C C Chiang¹, Sue M Vergamini², Ammar Husami³, Lisa Neumeier², Kathryn Quinn², Teresa Ellerhorst², Linda Sheppard², Carrie Gifford², David Buchbinder⁴, Avni Joshi⁵, Marianne Ifversen⁶, Gary I Kleiner⁷, James B Bussel⁸, Shanmuganathan Chandrakasan⁹, Robert D Pesek¹⁰, Tamara C Pozos¹¹, Melissa J Rose¹², Amy M Scurlock¹⁰, Kejian Zhang¹³, Yenan T Bryceson¹⁴, Jack Bleesing², Rebecca A Marsh²

Affiliations

¹ Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. Electronic address: sam.chiang@cchmc.org.
² Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
³ Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
⁴ CHOC Children's Hospital, Orange, Calif.
⁵ Division of Pediatric Allergy and Immunology, Mayo Clinic Childrens Center, Rochester, Minn.
⁶ Department of Pediatric and Adolescent Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
⁷ Department of Pediatrics, University of Miami Miller School of Medicine, Miami, Fla.
⁸ Weill Cornell Medical College, New York, NY.
⁹ Division of Bone Marrow Transplant, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Ga.
¹⁰ Arkansas Children's Hospital and the University of Arkansas for Medical Sciences, Little Rock, Ark.
¹¹ Pediatric Infectious Diseases and Immunology, Children's Minnesota, Minneapolis and St Paul, Minn.
¹² Nationwide Children's Hospital and the Ohio State University College of Medicine, Columbus, Ohio.
¹³ Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Coyote Bioscience, Campbell, Calif.
¹⁴ Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden; Broegelmann Research Laboratory, Department of Clinical Sciences, University of Bergen, Bergen, Norway.

PMID: 29729304
DOI: 10.1016/j.jaci.2018.04.017

No abstract available

Publication types

Letter

MeSH terms

Child
Child, Preschool
Female
Flow Cytometry / methods*
Humans
Infant
Infant, Newborn
Male
Mass Screening / methods
Sensitivity and Specificity
Wiskott-Aldrich Syndrome / diagnosis*
Wiskott-Aldrich Syndrome / genetics*
Wiskott-Aldrich Syndrome Protein / analysis
Wiskott-Aldrich Syndrome Protein / genetics*

Substances

Wiskott-Aldrich Syndrome Protein