Chronic prostatitis is a common male disease with a high incidence rate and a serious impact on the patients' quality of life. The pathogenesis of chronic prostatitis remains unclear though it is considered to be possibly related to infection, inflammation, and abnormal pelvic nerve muscle activity. Recently, a growing number of studies have reported immune imbalance and changes of inflammatory cytokines in patients with chronic prostatitis as well as a close correlation of abnormal immune response with the occurrence of diseases, pelvic pain symptoms, mental symptoms, hyperalgesia, and so on. This review summarizes the latest advances in the studies of immunologic mechanisms of chronic prostatitis.
慢性前列腺炎是男性常见疾病，发病率高，严重影响患者的生活质量。目前，慢性前列腺炎的发病机制仍不明确，可能与感染、炎症、盆底神经肌肉的异常活动等相关。近年来，越来越多的研究发现慢性前列腺炎患者存在免疫细胞比例失衡及炎性细胞因子的改变，并且免疫功能的失调与疾病的发生、骨盆疼痛症状的出现、精神症状、痛觉过敏等密切相关，本文就慢性前列腺炎中免疫细胞比例失衡及炎证因子的改变做一综述。.
Keywords: CD4+ T lymphocyte; immune imbalance; immunologic mechanism; chronic prostatitis.