A flexible quantile regression model for medical costs with application to Medical Expenditure Panel Survey Study

Stat Med. 2018 Jul 30;37(17):2645-2666. doi: 10.1002/sim.7670. Epub 2018 May 2.

Abstract

Medical costs are often skewed to the right and heteroscedastic, having a sophisticated relation with covariates. Mean function regression models with low-dimensional covariates have been extensively considered in the literature. However, it is important to develop a robust alternative to find the underlying relationship between medical costs and high-dimensional covariates. In this paper, we propose a new quantile regression model to analyze medical costs. We also consider variable selection, using an adaptive lasso penalized variable selection method to identify significant factors of the covariates. Simulation studies are conducted to illustrate the performance of the estimation method. We apply our method to the analysis of the Medical Expenditure Panel Survey dataset.

Keywords: adaptive lasso; high-dimensional covariates; hybrid stepwise approach; partially nonlinear; quantile regression; single index; variable selection.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Algorithms
  • Computer Simulation
  • Costs and Cost Analysis / methods*
  • Health Care Surveys
  • Health Expenditures
  • Humans
  • Models, Econometric*
  • Nonlinear Dynamics
  • Regression Analysis*
  • United States