Drugging homologous recombination: back to the future

Future Med Chem. 2018 Jun 1;10(11):1279-1281. doi: 10.4155/fmc-2018-0096. Epub 2018 May 2.
No abstract available

Keywords: DNA repair; cancer; homologous recombination; inhibitor; resistance.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Cell Line, Tumor
  • DNA Repair / drug effects*
  • Drug Resistance / drug effects*
  • Gene Expression Regulation / drug effects
  • Homologous Recombination*
  • Humans
  • Protein Kinase Inhibitors / pharmacology*
  • Signal Transduction
  • Ubiquitination / drug effects

Substances

  • Antineoplastic Agents
  • Protein Kinase Inhibitors