Primary breast leiomyosarcoma with metastases to the lung in a young adult: Case report and literature review

Melissa Amberger; Timothy Park; Bert Petersen; Gerard A Baltazar

doi:10.1016/j.ijscr.2018.04.010

Primary breast leiomyosarcoma with metastases to the lung in a young adult: Case report and literature review

Int J Surg Case Rep. 2018:47:34-37. doi: 10.1016/j.ijscr.2018.04.010. Epub 2018 Apr 16.

Authors

Melissa Amberger¹, Timothy Park², Bert Petersen³, Gerard A Baltazar⁴

Affiliations

¹ Division of General Surgery, Department of Surgery, SBH Health System, 4422 Third Avenue, Bronx, NY 10457 USA; School of Medicine, City University of New York, 160 Convent Avenue, New York, NY 10031 USA. Electronic address: mamberger@sbhny.org.
² Division of General Surgery, Department of Surgery, SBH Health System, 4422 Third Avenue, Bronx, NY 10457 USA; College of Osteopathic Medicine, New York Institute of Technology, PO Box 8000, Old Westbury, NY 11568 USA.
³ Division of Breast Surgery, Department of Surgery, SBH Health System, 4422 Third Avenue, Bronx, NY 10457 USA; School of Medicine, City University of New York, 160 Convent Avenue, New York, NY 10031 USA.
⁴ Division of General Surgery, Department of Surgery, SBH Health System, 4422 Third Avenue, Bronx, NY 10457 USA; College of Osteopathic Medicine, New York Institute of Technology, PO Box 8000, Old Westbury, NY 11568 USA; School of Medicine, City University of New York, 160 Convent Avenue, New York, NY 10031 USA.

Abstract

Introduction: Primary leiomyosarcomas of the breast are extremely rare. Because of this rarity, only a small number of studies have been published about the disease; diagnosis, treatment, and prognosis are not well-described. Our work has been reported in line with the SCARE criteria.

Presentation of case: We present a 20-year-old female with primary breast leiomyosarcoma who despite mastectomy, developed lung metastases three years later.

Discussion: We discuss the rarity of breast leiomyosarcoma and risk of metastatic disease even with treatment. We review the literature and provide an outline of available data to shed light on the best strategies to manage this aggressive disease.

Conclusion: Physicians and surgeons treating breast leiomyosarcoma must be vigilant of potential lung metastases in order to optimize short- and long-term oncologic outcomes.

Keywords: Breast; Cancer; Leiomyosarcoma; Metastatic; Neoplasm.