Medicinal components in Termitomyces mushrooms

Appl Microbiol Biotechnol. 2018 Jun;102(12):4987-4994. doi: 10.1007/s00253-018-8991-8. Epub 2018 Apr 27.

Abstract

Termitomyces is a genus of edible mushrooms commonly consumed in Africa and Asia among the mushrooms collected from the wild. Termitomyces mushrooms grow as symbionts in the termite nests, where they produce various enzymes to help termites digest lignocellulosic substrates. Many species of Termitomyces are used by different ethnic groups with ethnomedicinal knowledge. Bioactive components that Termitomyces mushrooms contain have potential uses as antioxidants, immunomodulators, antitumors, and antimicrobials. Termitomyces also has a potential for treating neurodegenerative disorders. Here, we review the bioactive compounds from Termitomyces species that have been isolated and assayed in vitro and/or in vivo for their medicinal properties.

Keywords: Cerebroside; Ergostane; Ethnomedicine; Fatty acid amide; Phenolic compound; Polysaccharide; Saponins; Serine protease.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / metabolism
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / metabolism
  • Antioxidants / chemistry
  • Antioxidants / metabolism
  • Asia
  • Immunologic Factors / chemistry
  • Immunologic Factors / metabolism
  • Isoptera / microbiology
  • Medicine, East Asian Traditional*
  • Termitomyces / chemistry*

Substances

  • Anti-Bacterial Agents
  • Antineoplastic Agents
  • Antioxidants
  • Immunologic Factors