Uukuniemi virus, Czech Republic

Ticks Tick Borne Dis. 2018 Jul;9(5):1129-1132. doi: 10.1016/j.ttbdis.2018.04.011. Epub 2018 Apr 20.

Abstract

Following the identification of severe fever with thrombocytopenia syndrome and Heartland viruses, the interest on tick-borne phleboviruses has increased rapidly. Uukuniemi virus has been proposed as a model for tick-borne phleboviruses. However, the number of available sequences is limited. In the current study we performed whole-genome sequencing on two Uukuniemi viral strains isolated in 2000 and 2004 from Ixodes ricinus ticks in the Czech Republic. Both strains cluster together with Potepli63 strain isolated in the country in 1963. Although the Czech strains were isolated many years apart, a high identity was seen at the nucleotide and amino acid levels, suggesting that UUKV has a relatively stable genome.

Keywords: Czech Republic; Ixodes ricinus; Phlebovirus; Uukuniemi virus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bunyaviridae Infections / epidemiology
  • Czech Republic / epidemiology
  • Genome, Viral
  • Ixodes / virology*
  • Tick-Borne Diseases / epidemiology
  • Tick-Borne Diseases / virology
  • Uukuniemi virus / genetics*
  • Uukuniemi virus / isolation & purification*
  • Whole Genome Sequencing