Adult Human Hippocampal Neurogenesis: Controversy and Evidence

Hyunah Lee; Sandrine Thuret

doi:10.1016/j.molmed.2018.04.002

Adult Human Hippocampal Neurogenesis: Controversy and Evidence

Trends Mol Med. 2018 Jun;24(6):521-522. doi: 10.1016/j.molmed.2018.04.002. Epub 2018 Apr 23.

Authors

Hyunah Lee¹, Sandrine Thuret²

Affiliations

¹ King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, London, UK.
² King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, London, UK. Electronic address: sandrine.1.thuret@kcl.ac.uk.

PMID: 29699864
DOI: 10.1016/j.molmed.2018.04.002

Abstract

The hippocampus has been described as one of the few sites in the mammalian brain capable of generating new cells continuously throughout life. Two recent studies that report contradicting findings on adult human hippocampal neurogenesis, however, reminds us of the caveats and challenges of studying this phenomenon in postmortem tissues.

Keywords: adult neurogenesis; hippocampus.

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MeSH terms

Adult
Animals
Child
Hippocampus*
Humans
Neurogenesis*