Abstract
Fungal strain FKJ-0025 was isolated from deep-sea sediment collected at the Wakamiko Caldera in Kagoshima Bay (water depth: 200 m). The fungal strain FKJ-0025 was identified as the genus Sarcopodium based on its morphology and internal transcribed spacer (ITS) sequence. Two new compounds, designated sarcopodinols A (1) and B (2), were isolated together with the known compound SF-227 (3).
Keywords:
Absolute configuration; PC screening; anti-tumor; deep-sea derived fungus.
MeSH terms
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / isolation & purification
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Antineoplastic Agents / pharmacology
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Aquatic Organisms / metabolism*
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Cell Line, Tumor
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Chromatography, Liquid
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Drug Screening Assays, Antitumor
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Fermentation
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Geologic Sediments / microbiology*
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Humans
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Hypocreales / metabolism*
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Mass Spectrometry
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Molecular Structure
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Polyphenols / chemistry
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Polyphenols / isolation & purification*
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Polyphenols / pharmacology
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Seawater
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Secondary Metabolism
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Spectrophotometry, Ultraviolet
Substances
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Antineoplastic Agents
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Polyphenols