Computer-Assisted Quantitative Assessment of Prostatic Calcifications in Patients with Chronic Prostatitis

Urol Int. 2018;100(4):450-455. doi: 10.1159/000486346. Epub 2018 Apr 26.

Abstract

Background: The aim of this study was the development of quantitative assessment of prostatic calcifications at prostatic ultrasound examination by the use of an image analyzer.

Materials and methods: A group of 82 patients was evaluated by medical history, physical, and transrectal ultrasound examination. Patients had a urethral swab, a 4-specimen study and culture of the seminal fluid. Patients were classified according to National Institute of Diabetes and Digestive and Kidney Diseases/National Institutes of Health. Subjective symptoms were scored by Chronic Prostatitis Symptom Index (CPSI) questionnaire. Ultrasound images were analyzed by the digital processing software Image J to quantitatively assess the presence of calcifications.

Results: Computer-assessed calcified areas were significantly higher in chronic bacterial prostatitis (n = 18; group II; 6.76 ± 8.09%) than in the chronic pelvic pain syndrome group IIIa (n = 26; 2.07 ± 1.01%) and IIIb (n = 38; 2.31 ± 2.18%). The area of calcification of the prostate was significantly related to the CPSI score for domains of micturition (r = 0.278, p = 0.023), Prostatic Specific Antigen values (r = 0341, p = 0.005), postvoiding residual urine (r = 0.262, p = 0.032), total prostate volume (r = 0.592, p = 0.000), and adenoma volume (r = 0.593; p = 0.000).

Conclusions: The presence of calcifications is more frequently observed in patients with chronic bacterial prostatitis and is related to urinary symptoms.

Keywords: Chronic pelvic pain syndrome; Computer assisted image analysis; Prostatic calcifications; Prostatitis.

MeSH terms

  • Adult
  • Calcinosis / complications*
  • Calcinosis / diagnosis*
  • Chronic Disease
  • Chronic Pain
  • Diagnosis, Computer-Assisted*
  • Humans
  • Image Processing, Computer-Assisted
  • Male
  • Middle Aged
  • Pelvic Pain
  • Prostate / physiopathology
  • Prostate-Specific Antigen / blood
  • Prostatitis / complications*
  • Prostatitis / diagnosis*
  • Prostatitis / microbiology
  • Semen
  • Severity of Illness Index
  • Surveys and Questionnaires
  • Ultrasonography
  • Urination

Substances

  • Prostate-Specific Antigen