Fate of the Aortic Arch Following Surgery on the Aortic Root and Ascending Aorta in Bicuspid Aortic Valve

Ann Thorac Surg. 2018 Sep;106(3):771-776. doi: 10.1016/j.athoracsur.2018.03.052. Epub 2018 Apr 23.

Abstract

Background: Recent guidelines support more aggressive surgery for aneurysms of the ascending aorta and root in patients with bicuspid aortic valve. However, the fate of the arch after surgery of the root and ascending aorta is unknown. We set out to assess outcomes following root and ascending aortic surgery and subsequent growth of the arch.

Methods: Between 2005 and 2016, 536 consecutive patients underwent surgery for aneurysm of the root and ascending aorta; 168 had bicuspid aortic valve. Patients with dissection were excluded. Arch diameter was measured before and after surgery, at 6 months and then annually.

Results: Of 168 patients, 127 (75.6%) had aortic root replacement and 41 (24.4%) had ascending replacement. Mean age was 57 ± 12.8 years, 82.7% were men, and 5 operations were performed during pregnancy. There was 1 (0.6%) hospital death. One (0.6%) patient had a stroke and 1 (0.6%) had resternotomy for bleeding. Median intensive care unit and hospital stays were 1 and 6 days, respectively. Follow-up was complete for 94% at a median of 5.9 years (range, 1 to 139 months). Aortic arch diameter was 2.9 cm preoperatively and 3.0 cm at follow-up. There was 97% freedom from reoperation and none of the patients required surgery on the arch.

Conclusions: Prophylactic arch replacement during aortic root and ascending aortic surgery in patients with bicuspid aortic valve is not supported. Our data do not support long-term surveillance of the rest of the aorta in this population.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Anastomosis, Surgical / methods
  • Aorta, Thoracic / physiopathology
  • Aorta, Thoracic / surgery
  • Aortic Aneurysm / diagnostic imaging
  • Aortic Aneurysm / mortality
  • Aortic Aneurysm / surgery*
  • Aortic Dissection / diagnostic imaging
  • Aortic Dissection / mortality*
  • Aortic Dissection / surgery*
  • Aortic Valve / abnormalities*
  • Aortic Valve / surgery
  • Bicuspid Aortic Valve Disease
  • Cohort Studies
  • Elective Surgical Procedures / methods
  • Elective Surgical Procedures / mortality
  • Emergencies
  • Female
  • Heart Valve Diseases / surgery*
  • Heart Valve Prosthesis Implantation / methods*
  • Hospital Mortality*
  • Humans
  • Kaplan-Meier Estimate
  • Length of Stay
  • Male
  • Middle Aged
  • Postoperative Complications / mortality
  • Postoperative Complications / physiopathology
  • Postoperative Complications / surgery
  • Prognosis
  • Proportional Hazards Models
  • Reoperation / methods
  • Reoperation / mortality
  • Retrospective Studies
  • Risk Assessment
  • Survival Rate
  • Treatment Outcome
  • United Kingdom