Antimicrobial Stewardship Program in a Pediatric Intensive Care Unit

Yuta Aizawa; Junichi Suwa; Hiroshi Higuchi; Kahoru Fukuoka; Mihoko Furuichi; Tetsuji Kaneko; Yoshihiko Morikawa; Kaoru Okazaki; Naoki Shimizu; Yuho Horikoshi

doi:10.1093/jpids/piy031

Antimicrobial Stewardship Program in a Pediatric Intensive Care Unit

J Pediatric Infect Dis Soc. 2018 Aug 17;7(3):e156-e159. doi: 10.1093/jpids/piy031.

Authors

Affiliations

¹ Division of Infectious Diseases, Department of Pediatrics, Tokyo Metropolitan Children's Medical Center, Japan.
² Department of Pharmacy, Tokyo Metropolitan Children's Medical Center, Japan.
³ Division of Microbiology, Department of Laboratory, Tokyo Metropolitan Children's Medical Center, Japan.
⁴ Clinical Research Support Center, Tokyo Metropolitan Children's Medical Center, Japan.
⁵ Division of Neonatology, Tokyo Metropolitan Children's Medical Center, Japan.
⁶ Division of Pediatric Critical Care Medicine, Department of Pediatric Emergency and Critical Care Medicine, Tokyo Metropolitan Children's Medical Center, Japan.

PMID: 29688433
DOI: 10.1093/jpids/piy031

Abstract

We conducted an antimicrobial stewardship program in a pediatric intensive care unit. An interrupted time-series analysis revealed a significant reduction in level and trend of days of therapy per 1000 patient-days for antipseudomonal agents. No increase in adverse patient outcomes was found.

MeSH terms

Anti-Bacterial Agents / therapeutic use*
Antimicrobial Stewardship*
Child
Drug Administration Schedule
Drug Resistance, Bacterial
Drug Utilization / statistics & numerical data
Humans
Intensive Care Units, Pediatric*
Interdisciplinary Communication
Interrupted Time Series Analysis
Japan
Length of Stay
Medical Staff, Hospital
Patient Outcome Assessment
Pseudomonas Infections / drug therapy
Referral and Consultation

Substances

Anti-Bacterial Agents