Phage Therapy for a Multidrug-Resistant Acinetobacter baumannii Craniectomy Site Infection

Stephanie LaVergne; Theron Hamilton; Biswajit Biswas; M Kumaraswamy; R T Schooley; Darcy Wooten

doi:10.1093/ofid/ofy064

Phage Therapy for a Multidrug-Resistant Acinetobacter baumannii Craniectomy Site Infection

Open Forum Infect Dis. 2018 Mar 23;5(4):ofy064. doi: 10.1093/ofid/ofy064. eCollection 2018 Apr.

Authors

Stephanie LaVergne¹, Theron Hamilton², Biswajit Biswas², M Kumaraswamy¹, R T Schooley¹, Darcy Wooten¹

Affiliations

¹ Department of Medicine, Division of Infectious Diseases, University of California, San Diego, La Jolla.
² Department of Genomics and Bioinformatics, Naval Medical Research Center-Frederick, Fort Detrick, Maryland.

Abstract

In the era of antibiotic resistance, alternative treatment options for multidrug-resistant bacterial infections are being explored. We present a case of multidrug-resistant Acinetobacter baumannii infection treated with bacteriophages. Clinical trials are needed to further investigate bacteriophage therapy as an option to treat multidrug-resistant bacterial infections.

Keywords: bacteriophage; multidrug resistance; phage.