Management of venous thromboembolism in cancer patients according to guidelines after educative measures

Bull Cancer. 2018 May;105(5):486-492. doi: 10.1016/j.bulcan.2018.01.019. Epub 2018 Apr 19.

Abstract

Guidelines for venous thromboembolism treatment with curative anticoagulation in cancer patients are poorly respected. Yet, venous thromboembolism is the second leading cause of death in cancer patients, after cancer progression. The aim of this study was to re-evaluate the application of these guidelines after the implementation of educational measures for patients and caregivers, and also to assess the acceptability and tolerance of treatment by patients. On the one hand, a prospective observational study conducted in cancer patients with VTE allowed to assess the rate of compliance to guidelines. These phone calls with patients also provided information on their perception of their treatment. On the other hand, surveys were sent to healthcare professionals before and after educative actions took place (information meetings and information sheets distribution) in order to evaluate the evolution of their knowledge about guidelines. Among the 110 patients included in the study, 71.8% received treatment according to guidelines: choice of the anticoagulant (low-molecular-weight heparin or antivitamin K if contraindicated) and right period of treatment. Among the patients, 84.1% were willing to continue treatment beyond 6 months. Healthcare professionals' knowledge about guidelines has increased significantly (from 20% to 42%) following the information meetings and information sheets distribution. These educative actions seem to have a positive impact on knowledge of the recommendations and their implementation.

Keywords: Cancer; Guidelines; Maladie thromboembolique veineuse; Recommandations; Venous thromboembolism.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anticoagulants / therapeutic use*
  • Caregivers / education*
  • Clinical Competence / standards
  • Clinical Competence / statistics & numerical data
  • Heparin, Low-Molecular-Weight / therapeutic use
  • Humans
  • Medical Staff, Hospital / statistics & numerical data
  • Middle Aged
  • Neoplasms / complications*
  • Neoplasms / psychology
  • Nursing Staff, Hospital / statistics & numerical data
  • Patient Acceptance of Health Care / psychology
  • Patient Acceptance of Health Care / statistics & numerical data*
  • Patient Education as Topic*
  • Pharmacists / statistics & numerical data
  • Practice Guidelines as Topic*
  • Prospective Studies
  • Venous Thromboembolism / complications
  • Venous Thromboembolism / drug therapy*

Substances

  • Anticoagulants
  • Heparin, Low-Molecular-Weight