Corneal fibroma: An uncommon stromal tumor

Indian J Ophthalmol. 2018 May;66(5):699-701. doi: 10.4103/ijo.IJO_936_17.

Abstract

A 56-year-old male patient presented with a slow-growing, elevated, smooth, white corneal mass. The mass was excised by performing an alcohol-assisted keratoepitheliectomy and sent for histopathological examination. Subepithelially, closely packed spindle cells in "feather-stitched" or storiform pattern were seen. Immunohistochemically, the cells stained negatively for CD-34 and S-100 and focal positivity was seen for vimentin. Based on the morphology and immunochemical staining, a diagnosis of corneal fibroma was made. No recurrence was seen. Corneal fibroma is an exceedingly rare, benign tumor and possibly lies on the same spectrum as corneal keloid and hypertrophic cicatrix. Surgical resection is usually curative.

Keywords: Cicatrix; corneal keloid; dermoid; limbus; neoplasm; ocular surface squamous neoplasm.

Publication types

  • Case Reports

MeSH terms

  • Corneal Diseases / diagnosis*
  • Corneal Diseases / surgery
  • Corneal Stroma / pathology*
  • Corneal Stroma / surgery
  • Fibroma / diagnosis*
  • Fibroma / surgery
  • Humans
  • Male
  • Middle Aged
  • Ophthalmologic Surgical Procedures / methods*
  • Photomicrography