Wettability (hydrophobicity and hydrophilicity) is of fundamental importance in physical, chemical, and biological behaviors, resulting in widespread interest. Herein, by modulating surface curvature, we observed a reversible hydrophobic-hydrophilic transition on a model referred to a platinum surface. The underlying mechanism is revealed to be the competition between strong water-solid attraction and interfacial water orderliness. On the basis of the competition, we further propose an equation of wetting transition in the presence of an ordered interfacial liquid. It quantitatively reveals the relation of solid wettability with interfacial water orderliness and solid surface curvature, which can be used for predicting the critical point of the wetting transition. Our findings thus provide an innovative perspective on the design of a functional device demonstrating a reversible wettability transition and even a molecular-level understanding of biological functions.