Hepatobiliary and Pancreatic: Primary acinar cell carcinoma of the liver showing good response to chemotherapy

J Gastroenterol Hepatol. 2018 May;33(5):977. doi: 10.1111/jgh.14063.

Abstract

A 48-year old man with no history of liver disease or alcohol addiction developed jaundice, itching and dark urine without any symptom of abdominal pain.

A CT examination revealed the presence of a liver mass extending between segments 4, 5 and 8 that was found to be an acinar cell carcinoma at biopsy. The primary hepatic origin was confirmed mainly excluding a primary pancreatic tumor by diagnostic work-up.

Since the lesion was considered unresectable at the time of the diagnosis, the patient underwent to Xeloda and oxaliplatin neoadjuvant chemotherapy, with progressive reduction in size of the mass as a sign of good response to therapy.

Publication types

  • Case Reports

MeSH terms

  • Acinar Cells / pathology
  • Antineoplastic Agents / administration & dosage
  • Biopsy / methods
  • Capecitabine / administration & dosage*
  • Carcinoma, Acinar Cell* / diagnosis
  • Carcinoma, Acinar Cell* / pathology
  • Carcinoma, Acinar Cell* / therapy
  • Diagnosis, Differential
  • Humans
  • Liver Neoplasms* / diagnosis
  • Liver Neoplasms* / pathology
  • Liver Neoplasms* / therapy
  • Liver* / diagnostic imaging
  • Liver* / pathology
  • Male
  • Middle Aged
  • Oxaliplatin / administration & dosage*
  • Pancreatic Neoplasms / diagnosis
  • Tomography, X-Ray Computed / methods*
  • Treatment Outcome
  • Ultrasonography / methods

Substances

  • Antineoplastic Agents
  • Oxaliplatin
  • Capecitabine